Immunological assessment of SARS-CoV-2 infection in pregnancy from diagnosis to delivery: A multicentre prospective study.
Kate GlennonJennifer DonnellySusan KnowlesFionnuala M McAuliffeAlma O'ReillySiobhan CorcoranJennifer WalshRoger McMorrowTess HigginsLucy BolgerSusan ClintonSarah O'RiordanAlexander StartDoireann RocheHelena BartelsCiara MaloneKarl McAuleyAnthony McDermottRosanna InzitariColm P F O'DonnellFergal MaloneShane HigginsCillian De GascunPeter DoranDonal J BrennanPublished in: PloS one (2021)
Using two independent serological assays, we present a comprehensive illustration of the antibody response to SARS-CoV-2 in pregnancy, and show a low prevalence of asymptomatic SARS-CoV2. Transplacental migration of anti-SARS-CoV-2 antibodies was identified in cord blood of women who demonstrated antenatal anti-SARS-CoV-2 antibodies, raising the possibility of passive immunity.