Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19.
Norma MaugeriRebecca De LorenzoNicola ClementiRoberta Antonia DiottiElena CriscuoloCosmo GodinoCristina TresoldiBio Angels For Covid-BioB Study GroupChiara BoniniMassimo ClementiNicasio ManciniFabio CiceriPatrizia Rovere-QueriniAngelo A ManfrediPublished in: Journal of thrombosis and haemostasis : JTH (2021)
Hence, an early and intense platelet activation, which is reproduced by stimulating platelets in vitro with SARS-CoV-2, characterizes COVID-19 and could contribute to the inflammatory and hemostatic manifestations of the disease.