Meta-analysis of the rs243865 MMP-2 polymorphism and age-related macular degeneration risk.

Ricardo Usategui-MartínSalvador Pastor-IdoateAntonio J ChamorroItziar Fernandez Iván Fernández-BuenoMiguel Marcos-MartínRogelio González-SarmientoJosé Carlos Pastor

Published in: PloS one (2019)

The rs243865 MMP-2 polymorphism was not associated with an increased risk of developing AMD. The MMP-2 (-1306 C>T) promoter variant is unlikely to have a major role in AMD risk susceptibility.

Keyphrases

age related macular degeneration
systematic review
cell migration
dna methylation
gene expression
transcription factor
meta analyses