Eleven-month SARS-CoV-2 binding antibody decay, and associated factors, among mRNA vaccinees: implications for booster vaccination.
Michael Asamoah-BoahengBrian GrunauScott HaigMohammad Ehsanul KarimTracy KirkhamPascal M LavoieSadaf SediqiSteven J DrewsSheila F O'BrienVilte BarakauskasAna Citlali MarquezAgatha JassemDavid M GoldfarbPublished in: Access microbiology (2023)
Antibody levels declined after the initial mRNA series with a half-life of 94 days, plateauing at 295 days. These findings may inform the timing of booster vaccine doses and identifying individuals with faster antibody decay.