Molecular Detection of Hemoglobin O-Arab in the Sudanese Population.

Izzeldin Elbashir Tagwa Yousif Elsayed Yousif

Published in: International journal of general medicine (2023)

The frequency of Hb-O Arab gene mutations was determined among Sudanese sickle cell disease patients, and the results have shown a (5%) frequency of Hb-O Arab mutation. The study result is the first molecular confirmation of co-inherited Hb-O Arab/sickle cell disease clinical condition in Sudan. The results raise the importance of extended studies of other sickle variant conditions.

Keyphrases

sickle cell disease
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
patient reported