Effect of Co-administration of Bumetanide and Phenobarbital on Seizure Attacks in Temporal Lobe Epilepsy.

Reza RahmanzadehSoraya MehrabiMahmood BaratiMilad AhmadiFereshteh GolabSareh KazmiMohammad Taghi JoghataeiMorteza SeifiMazaher Gholipourmalekabadi

Published in: Basic and clinical neuroscience (2018)

The combination of bumetanide with phenobarbital increases the inhibition of SE and maximizes the potential of GABA signaling pathway, and can be considered as an effective therapeutic strategy in patients with epilepsy.

Keyphrases

temporal lobe epilepsy
signaling pathway
pi k akt
epithelial mesenchymal transition
induced apoptosis
cell proliferation
oxidative stress