A Proposed Inflammatory Score of Circulating Cytokines/Adipokines Associated with Resistant Hypertension, but Dependent on Obesity Parameters.

Ana Paula Cabral de Faria Alessandra Mileni Versuti Ritter Carolina Souza Gasparetti Nathália Batista Corrêa Veridiana Brunelli Aurelio Rochael Almeida Nayara Fraccari Pires Rodrigo Modolo Heitor Moreno Júnior

Published in: Arquivos brasileiros de cardiologia (2019)

A state of subclinical inflammation defined by an IS including TNF-alpha, IL-6, IL-8, IL-10, leptin and adiponectin is associated with obese RHTN. In addition, this score correlates with obesity parameters, independently of hypertensive status. The IS may be used for the evaluation of conditions involving low-grade inflammation, such as obesity-related RHTN. Indeed, it also highlights the strong relationship between obesity and inflammatory process.

Keyphrases

metabolic syndrome
insulin resistance
weight loss
low grade
type diabetes
oxidative stress
high fat diet induced
weight gain
blood pressure
adipose tissue
bariatric surgery
high grade
rheumatoid arthritis
skeletal muscle
body mass index
arterial hypertension