A New Chemometrically Assisted UV Spectrophotometric Method for Simultaneous Determination of Tamsulosin and Dutasteride in Their Pharmaceutical Mixture.
Khalid A M AttiaAhmed SeragSherif M EidAhmed Emad F AbbasPublished in: Journal of AOAC International (2022)
Overall, this work presents powerful simple, selective, sensitive, and precise methods for simultaneous quantification of TAM/DUT in their dosage form with satisfactory results. The predictive ability and accuracy of the developed methods offer the opportunity to be employed as a quality control technique for the routine analysis of TAM/DUT when chromatographic instruments are not available.
Keyphrases
- simultaneous determination
- quality control
- liquid chromatography tandem mass spectrometry
- benign prostatic hyperplasia
- high performance liquid chromatography
- tandem mass spectrometry
- lower urinary tract symptoms
- ultra high performance liquid chromatography
- liquid chromatography
- solid phase extraction
- clinical practice
- mass spectrometry
- high resolution mass spectrometry
- patient reported outcomes