Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.
Marie NolletRichard BachelierAhmad JoshkonWaël TraboulsiAmandine MahieuxAnais MoyonAlexandre MullerIndumathi SomasundaramStéphanie SimonciniFranck PeirettiAurélie S LeroyerBenjamin GuilletBrigitte GranelFrançoise Dignat-GeorgeNathalie BardinAlexandrine Foucault-BertaudMarcel Blot-ChabaudPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
Variants of sCD146, and in particular the novel I5-13-sCD146 splice variant, could constitute novel biomarkers and/or molecular targets for the diagnosis and treatment of SSc and other angiogenesis- or fibrosis-related disorders.