Reduced Myocardial Perfusion Reserve in Type 2 Diabetes Is Caused by Increased Perfusion at Rest and Decreased Maximal Perfusion During Stress.

Martin Heyn SørensenAnnemie S BojerJulie R N PontoppidanDavid A BroadbentSven PleinPer L MadsenPeter Gæde

Published in: Diabetes care (2020)

Patients with type 2 diabetes have higher global MBF at rest and lower maximal MBF during vasodilator-induced stress than control subjects. Reduced MBF during stress is associated with diabetes complications (albuminuria and retinopathy) and is inversely correlated with diffuse myocardial fibrosis.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
heart rate
resistance training
contrast enhanced
low grade
risk factors
heart failure
magnetic resonance imaging
insulin resistance
computed tomography
body composition
adipose tissue
skeletal muscle
blood pressure
high grade