Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas.

Ernest J NelsonMaria A GubbiottiAlicia M CarlinMac Lean P Nasrallah Vivianna M Van Deerlin Sarah E Herlihy

Published in: Molecular diagnosis & therapy (2023)

In summary, we report that this RT-PCR assay can reliably be performed on formalin-fixed paraffin-embedded specimens and has a faster turnaround time than sequencing assays and can be clinically implemented for determination of IDH mutation status for patients with glioma.

Keyphrases

clinical evaluation
low grade
high throughput
high grade
wild type
solid phase extraction
high resolution
real time pcr