Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans.
Dike B OjjiBongani MayosiVeronica FrancisMotasim BadriVictoria CorneliusWynand SmytheNicky KramerFelix BarasaAlbertino DamascenoAnastase DzudieErika JonesCharles MondoOkechukwu OgahElijah OgolaMahmoud U SaniGabriel L ShedulGrace ShedulBrian RaynerIkechi G OkpechiKaren SliwaNeil Poulternull nullPublished in: The New England journal of medicine (2019)
These findings suggest that in black patients in sub-Saharan Africa, amlodipine plus either hydrochlorothiazide or perindopril was more effective than perindopril plus hydrochlorothiazide at lowering blood pressure at 6 months. (Funded by GlaxoSmithKline Africa Noncommunicable Disease Open Lab; CREOLE ClinicalTrials.gov number, NCT02742467.).