Serotonin mediates the panicolytic-like effect of oxytocin in the dorsal periaqueductal gray.
Thatiane De Oliveira SergioAlana Tercino FriasHeloisa Helena Vilela-CostaDanielle Cg De OliveiraAntônio W ZuardiHélio ZangrossiPublished in: Journal of psychopharmacology (Oxford, England) (2020)
OT and 5-HT in the dPAG interact in the regulation of panic- and anxiety-related defensive responses. These findings open new perspectives for the development of novel therapeutic strategies for the treatment of anxiety disorders.