Older Age is Associated with Higher Dolutegravir Exposure in Plasma and Cerebrospinal Fluid of People Living with HIV.

Andrea CalcagnoJosé MoltóAlberto BorghettiCristina GervasoniMaurizio MilesiMarta ValleValeria AvataneoChiara AlcantariniFrancesc Pla-JuncaMattia TrunfioAntonio D'AvolioSimona Di GiambenedettoDario CattaneoGiovanni Di PerriStefano Bonora

Published in: Clinical pharmacokinetics (2021)

We observed an increase in dolutegravir exposure in serum and in cerebrospinal fluid in older patients living with human immunodeficiency virus.

Keyphrases

cerebrospinal fluid
human immunodeficiency virus
antiretroviral therapy
hiv infected
hiv infected patients
hepatitis c virus
hiv positive
hiv aids
physical activity
middle aged
community dwelling