Revisiting the Evidence Base for Modern Day Practice of the Treatment of Toxoplasmic Encephalitis: A Systematic Review and Meta-Analysis.
Connor ProstyRyan HanulaYossef LevinIsaac I BogochEmily G McDonaldTodd C LeePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
TMP-SMX appears to be as effective and safer than the pyrimethamine-containing regimens for TE. These findings support modern RCTs comparing TMP-SMX to P-S or P-C and a revisiting of the guidelines.