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Impact of short-term hydrocortisone intake on pituitary and adrenal function in healthy young male subjects.

Katia CollompVirgile AmiotBarbara RobinMagnus EricssonCorinne Buisson
Published in: Endocrine (2020)
Once-daily oral therapeutic administration of hydrocortisone for 5 days altered adrenal DHEA secretion by inhibiting pituitary ACTH, but this effect seemed transient without significant impairment of basal adrenal or pituitary function 24 h after administration. Given the high correlations between plasma and saliva, saliva samples may be offered as a sensitive surrogate for blood sampling to estimate adrenal and pituitary function.
Keyphrases
  • growth hormone
  • physical activity
  • body mass index
  • weight loss