A limited and intermittent access to a high-fat diet modulates the effects of cocaine-induced reinstatement in the conditioned place preference in male and female mice.

Francisco Ródenas-GonzálezMaría Del Carmen Blanco-GandíaMaría PascualIrene MolariConsuelo GuerriJosé Miñarro LópezMarta Rodríguez-Arias

Published in: Psychopharmacology (2021)

These results support that palatable food could act as an alternative reward to cocaine, accelerating extinction and blocking reinstatement, these effects being sex specific.

Keyphrases

high fat diet
insulin resistance
adipose tissue
prefrontal cortex
high fat diet induced
high glucose
diabetic rats
high intensity
type diabetes
metabolic syndrome
drug induced
skeletal muscle
endothelial cells
climate change
stress induced