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Comprehensive analysis of scRNA-Seq and bulk RNA-Seq reveals dynamic changes in the tumor immune microenvironment of bladder cancer and establishes a prognostic model.

Zhiyong TanXiaorong ChenJieming ZuoShi FuHaifeng WangJiansong Wang
Published in: Journal of translational medicine (2023)
By integrating scRNA-seq and bulk RNA-seq data, we constructed a novel prognostic model to predict the survival of BLCA patients. The risk score is a promising independent prognostic factor that is closely correlated with the immune microenvironment and clinicopathological characteristics.
Keyphrases
  • rna seq
  • prognostic factors
  • single cell
  • stem cells
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • wastewater treatment
  • dna methylation
  • big data
  • electronic health record