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NOP Receptor Antagonists Decrease Alcohol Drinking in the Dark in C57BL/6J Mice.

Gloria BrunoriMichelle WegerJennifer SchochKatarzyna Targowska-DudaMegan BarnesAnna Maria BorrutoLinda M Rorick-KehnNurulain T ZaveriJohn E PintarRoberto CiccocioppoLawrence TollAndrea Cippitelli
Published in: Alcoholism, clinical and experimental research (2019)
The present results suggest that NOP receptor inhibition rather than activation may represent a valuable approach for treatment of AUD characterized by excessive alcohol consumption such as binge drinking.
Keyphrases
  • alcohol consumption
  • high fat diet induced
  • weight gain
  • physical activity
  • skeletal muscle
  • body mass index
  • binding protein