Alternative metrics for characterizing longer-term clinical outcomes in difficult-to-treat depression: I. Association with change in quality of life.
Harold A SackeimA John RushTeresa GrecoMei JiangSarah BadejoMark T BunkerScott T AaronsonCharles R ConwayKoen DemyttenaereAllan H YoungR Hamish McAllister-WilliamsPublished in: Psychological medicine (2023)
Revision is needed in the metrics used to quantify symptomatic change in DTD with consideration of INT time-based measures as primary or secondary outcomes. Metrics based on remission status may not be useful.