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Non-muscle myosins control the integrity of cortical radial glial endfeet.

Li WangArnold R Kriegstein
Published in: PLoS biology (2023)
Radial glial cells, the stem cells of the cerebral cortex, extend a long basal fiber that ends in basal endfeet. A new study in PLOS Biology found that non-muscle myosins control basal endfoot integrity to regulate interneuron organization.
Keyphrases
  • stem cells
  • skeletal muscle
  • induced apoptosis
  • neuropathic pain
  • cell cycle arrest
  • subarachnoid hemorrhage
  • functional connectivity
  • cell therapy
  • endoplasmic reticulum stress
  • mesenchymal stem cells
  • cerebral ischemia