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The Role of Extracorporeal Blood Purification in the Treatment of a Patient with Lemierre's Syndrome.

Lana MaricicDamir MihićTajana TurkDomagoj LoinjakVedran Zubčić
Published in: Case reports in medicine (2022)
Lemierre's syndrome refers to the septic thrombophlebitis of the internal jugular vein. The condition typically begins with an oropharyngeal infection and frequently involves inflammation within the wall of the vein, infected thrombus within the lumen, surrounding soft tissue inflammation, persistent bacteremia, and septic emboli. Lemierre's syndrome is a rare disease; it occurs most commonly in otherwise healthy young adults. The most common etiologic agent is Fus obacterium necrophorum . We present a case of Lemierre's syndrome in a young girl and the role of extracorporeal method of blood purification with continuous venous hemodiafiltration with the use of a highly adsorptive membrane (AN69 HeprAN), thus achieving the combined elimination of cytokines and endotoxins. The use of advanced methods, along with an antibiotic and surgical treatment, will certainly help reduce mortality in this syndrome.
Keyphrases
  • case report
  • young adults
  • oxidative stress
  • acute kidney injury
  • cardiovascular disease
  • coronary artery disease
  • combination therapy
  • multidrug resistant