Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.

Brianna J StubbsElizabeth B StephensChatura SenadheeraSawyer PeraltaStephanie Roa-DiazLaura AlexanderWendie Silverman-MartinThelma Y GarciaMichi YukawaJenifer MorrisTraci M BlonquistJames B JohnsonJohn C Newman

Published in: The journal of nutrition, health & aging (2024)

This KE was safe and well-tolerated in this study of healthy older adults. These results provide an initial foundation for use of KEs in clinical research with older adults.

Keyphrases

physical activity
placebo controlled
double blind
clinical trial
study protocol
phase ii
ionic liquid
phase iii
phase ii study