Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens.
Irene OliveraIñaki EtxeberríaElixabet BolañosMaría Gato-CañasIgnacio MeleroPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
T-cell recognizable p53 hotspot mutations offer opportunities for immunotherapy and immune monitoring. Recognition of p53 mutations by peripheral blood CD8 and CD4 T lymphocytes has been revealed.See related article by Malekzadeh et al., p. 1267.