Inflammation biomarkers in suicide attempts and their relation to abuse, global functioning and cognition.

Jessica Fernández-SevillanoItxaso González-OrtegaKarina MacDowellIñaki ZorrillaMaría Purificación LópezPhilippe CourtetAndrea GabilondoMónica Martínez-CengotitabengoaJuan Carlos LezaPilar A SáizAna González-Pinto

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)

Recent and distant suicidal behaviour is associated with elevated IL-6 levels, which may be influenced by stressful and traumatic experiences. Elevated concentrations of IL-6 could have a negative impact on attention, increasing suicide risk. More research is needed to clarify the role of cytokines in suicide-related features to explore novel treatments and more effective preventive interventions.

Keyphrases

spinal cord injury
oxidative stress
lymph node
working memory
mental health
physical activity
mild cognitive impairment
white matter
drug induced