Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats.

Samireh GhafouriYaghoub FathollahiSaeed SemnanianAmir ShojaeiAzam AsgariAzin Ebrahim AminiJavad Mirnajafi-Zadeh

Published in: PloS one (2019)

The application of LFS in kindled animals restored LTP induction in both EPSPs and IPSPs, and returned the threshold intensity for induction of EPSCs, IPSCs and gene expression to similar levels as controls.

Keyphrases

deep brain stimulation
gene expression
parkinson disease
obsessive compulsive disorder
dna methylation