Effects of 1-month withdrawal of ventilatory support in hypercapnic myotonic dystrophy type 1.
Fergal J O'DonoghueJean-Christian BorelYves DauvilliersPatrick LevyRenaud TamisierJean-Louis PépinPublished in: Respirology (Carlton, Vic.) (2017)
DM1 patients derive little benefit in symptoms or quality of life from NIV. Nocturnal and diurnal ventilatory functions deteriorate slightly off NIV for 1 month, but this does not appear to be due to changes in HCVR or respiratory function. HCVR changes may be of primary CNS origin given stability on or off NIV.
Keyphrases
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- prognostic factors
- peritoneal dialysis
- obstructive sleep apnea
- blood brain barrier
- intensive care unit
- early onset
- type diabetes
- adipose tissue
- skeletal muscle
- patient reported
- weight loss
- extracorporeal membrane oxygenation
- insulin resistance
- acute respiratory distress syndrome
- mechanical ventilation