Increased levels of circulating soluble CD226 in multiple sclerosis.
Saniya KariFlorence BucciarelliThibault AnglesAnne-Cecile OsterPauline CauboueKarl LavioletteMadeline MougenotElena MorandiIsabelle BernardBeatrice PignoletChloé BostJoelle ThomasLeonor NogueiraAbdelhadi SaoudiRoland LiblauAnne L AstierPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
Our data suggest that T-cell activation leads to release of sCD226 that could promote inflammation and raises the possibility of using sCD226 as a biomarker for neuroinflammation.