Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer.
María Paula MarksCarla Alejandra GiménezLuciana IsajaMariana Belén VeraFrancisco Raúl BorzoneFederico Pereyra-BonnetLeonardo RomoriniGuillermo Agustín Videla-RichardsonNorma Alejandra ChasseingJuan Carlos CalvoLuciano VellonPublished in: Journal of cancer research and clinical oncology (2024)
HMGCR induces a stem-like phenotype in BC cells of epithelial nature, thus affecting tumor initiation, progression and statin sensitivity.