Exploring the Therapeutic Mechanisms of Huzhang-Shanzha Herb Pair against Coronary Heart Disease by Network Pharmacology and Molecular Docking.

Dan Li Longtao Liu Shengjie Yang Yanwei XingLimin PanRan ZhaoYixi ZhaoGuirui Huang Min Wu

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

Using network pharmacology, we provide new clues on the potential mechanism of action of HSHP in the treatment of CHD, which may be closely related to the fluid shear force, lipid metabolism, and inflammatory response.

Keyphrases

molecular docking
inflammatory response
molecular dynamics simulations
lipopolysaccharide induced
single molecule
toll like receptor
combination therapy
risk assessment