Exploring the function of factor XIII free B subunit: Interactions with complement factors and a novel approach to identify potential binding partners.

Bojun LiClément BechtlerLorenz JennyDaniel RicklinVerena Schroeder

Published in: Research and practice in thrombosis and haemostasis (2022)

Our study reveals that free FXIII-B has no direct role in regulating the complement system, despite a structural similarity to major complement regulators. Further studies are needed to validate α2MG as a binding partner and explore potential functional consequences of this binding.

Keyphrases

dna binding
binding protein
transcription factor
hiv testing
human health
risk assessment
human immunodeficiency virus
climate change
hiv infected