Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study.

In Ae KimJong Sik LeeHee Joung KimWan Seop KimKye Young Lee

Published in: BMC cancer (2018)

CSD is an important predictive and prognostic factor in patients with EGFR-mutated lung adenocarcinoma, and associated smoking-related gene signatures might affect the outcomes.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
prognostic factors
tyrosine kinase
smoking cessation
genome wide
gene expression
type diabetes
copy number
skeletal muscle
transcription factor
weight loss