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Post-radiotherapy vascular lesions of the breast: immunohistochemical and molecular features of 74 cases with long-term follow-up and literature review.

Angelo G CorradiniSofia AsioliLuca MorandiMaurizio BrottoAlberto RighiMarica IommiClaudio AgostinelliPaola RucciSilvia AsioliAnna SapinoGiuseppe VialeMaria Pia Foschini
Published in: Histopathology (2020)
Our findings confirm that BLAP and AVL have a good prognosis, and that post-RT AS prognosis is strongly related to histological grading. On molecular analysis, AVL and post-RT AS shared HRAS and hTERT mutations, suggesting a relationship between the two lesions.
Keyphrases
  • early stage
  • radiation therapy
  • case report
  • squamous cell carcinoma