Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.
Derek B ArcherJaclyn M EissmanShubhabrata MukherjeeMichael L LeeSeo-Eun ChoiPhoebe ScollardEmily H TrittschuhJesse B MezWilliam S BushBrian W KunkleAdam C NajKatherine A Giffordnull nullnull nullnull nullMichael L CuccaroMargaret A Pericak-VanceLindsay A FarrerLi-San WangGerard D SchellenbergRichard P MayeuxJonathan L HainesAngela L JeffersonWalter A KukullC Dirk KeeneAndrew J SaykinPaul M ThompsonEden R MartinDavid A BennettLisa L BarnesJulie A SchneiderPaul K CraneLogan DumitrescuTimothy J HohmanPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Late-life memory has high heritability that is similar across ancestries. We discovered four novel variants associated with late-life memory. We identified four novel genes associated with late-life memory. Late-life memory shares genetic architecture with psychiatric/autoimmune traits.