Low hemoglobin causes hematoma expansion and poor intracerebral hemorrhage outcomes.
Azzurra CottarelliRayan MamoonRobin JiEric MaoAmelia BoehmeAditya KumarSandy SongValentina AllegraSabrina V SharmaElisa E KonofagouVadim SpektorJia GuoE Sander ConnollyPadmini SekarDaniel WooDavid J RohPublished in: bioRxiv : the preprint server for biology (2024)
These results, in a human cohort and a mouse model, provide novel evidence suggesting that anemia has causal roles in HE and poor ICH outcomes. Additional studies are required to clarify whether correcting anemia can improve these outcomes.