A population pharmacokinetic model for escitalopram and its major metabolite in depressive patients during the perinatal period: Prediction of infant drug exposure through breast milk.
Etienne WeisskopfMonia GuidiCéline J FischerMyriam Bickle-GrazEtienne BeaufilsKim An NguyenMathilde Morisod HarariSylvie RouillerSophie RothenburgerPascal GaucherandBehrouz KassaiCristina Borradori TolsaManuella EpineyJean-François TolsaYvan VialJean-Michel HascoëtOlivier ClarisChin Bin EapAlice PanchaudChantal CsajkaPublished in: British journal of clinical pharmacology (2020)
The moderate between-subject variability in milk concentration of SCIT and the limited exposure to escitalopram through breast milk observed provide reassurance for treated mothers of breastfed healthy infants.