Influence of IL-β, IL-1RN, and TNF-α variants on the risk of acetylsalicylic acid-induced upper gastrointestinal bleeding: a case-control study.

Marcela Forgerini Cleslei Fernando Zanelli Sandro Roberto Valentini Patrícia de Carvalho Mastroianni

Published in: Einstein (Sao Paulo, Brazil) (2024)

This study aimed to explore pharmacogenomics biomarkers in low-dose acetylsalicylic acid users. Our data suggest that the presence of IL-1β, IL-1RN, and TNF-α variants was not associated with an increased risk of upper gastrointestinal bleeding.

Keyphrases

low dose
rheumatoid arthritis
high dose
emergency department
gene expression
dna methylation
big data
artificial intelligence
adverse drug
drug induced