Comorbidity among HHT patients and their controls in a 20 years follow-up period.
Katrine Saldern AagaardAnette Drøhse KjeldsenPernille Mathiesen TørringAnders GreenPublished in: Orphanet journal of rare diseases (2018)
Based on this study Danish HHT patients had an increased comorbidity of infections in joints and bones and of bleeding episodes. However, the incidence of thromboembolisms, cerebral abscesses and other conditions commonly considered related to HHT was comparable between the patients and the controls. The patients included in this study were closely monitored at a highly specialised HHT Centre where they received relevant diagnostic evaluation, treatment and counselling. Since this is assumed to benefit the overall health of the patients, it may explain why these patients were less prone to comorbidity than other studies have suggested.
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