Gut environment changes due to androgen deprivation therapy in patients with prostate cancer.
Akimasa KureTomoya TsukimiChiharu IshiiWanping AwNozomu ObanaGaku NakatoAkiyoshi HirayamaHaruna KawanoToshiyuki ChinaFumitaka ShimizuMasayoshi NagataShinji IsotaniSatoru MutoShigeo HorieShinji FukudaPublished in: Prostate cancer and prostatic diseases (2022)
The decline in testosterone levels resulted in detrimental changes in gut microbiota. This dysbiosis may contribute to an increase in frailty and an increased risk of adverse outcomes in patients with prostate cancer.