Reduced Numbers and Impaired Function of Regulatory T Cells in Peripheral Blood of Ischemic Stroke Patients.

Johanna RuhnauJuliane SchulzeBettina von SarnowskiMarie HeinrichSönke LangnerChristian PötschkeAnika WildenChristof KesslerBarbara M BrökerAntje Vogelgesang Alexander Dressel

Published in: Mediators of inflammation (2016)

We demonstrate a loss of active FoxP3(+)CD39(+) Tregs from stroke patient's peripheral blood. The suppressive Treg function of remaining Tregs is impaired after stroke.

Keyphrases

regulatory t cells
peripheral blood
dendritic cells
end stage renal disease
atrial fibrillation
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
case report
patient reported outcomes
blood brain barrier
brain injury