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The association of polymorphisms in TNF and ankylosing spondylitis in common population: a meta-analysis.

Naiwen HuXi ChenShanjuan WangGangying YuanQinqin WangHuae ShuHongsheng Sun
Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2021)
Our meta-analysis suggests that TNF-α polymorphisms at positions - 238, - 308, - 850, - 1031 and rs769178 could have an influence on ankylosing spondylitis susceptibility in the total population. But there is no association of the TNF-376, TNF-857, TNF-863 polymorphisms with ankylosing spondylitis. Some results in the subgroups are not consistent with those in the total population.
Keyphrases
  • ankylosing spondylitis
  • rheumatoid arthritis
  • disease activity
  • systematic review
  • systemic lupus erythematosus