To advance the study of children's knowledge and understanding of disease, we devised a methodology for assessing key features of intuitive theories laid out by Wellman and Gelman (1998). We then assessed a disease-relevant biological ontology, causal propositions involving unobservables, and coherence in explanations of influenza offered by children aged 8 to 13. Use of disease-relevant terms and mention of propositions in a biological theory of flu causality, although not coherence or connectedness of ideas, increased with age. Measures were moderately correlated with one another and with a traditional Piagetian measure of level of disease understanding, each contributing uniquely to the characterization of children's thinking. In multiple regression analyses, scores were highest for older children, Latino/minority children, and children of more educated parents with other factors controlled. Specific gaps in children's intuitive theories are identified to guide theory-based interventions aimed at helping children understand and protect themselves from infectious diseases.
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