Clinical profiles of subsequent stages in bipolar disorder: Results from the Dutch Bipolar Cohort.
Afra van der MarktUrsula M H KlumpersAnnemieke DolsMarco P M BoksAnnabel VreekerAartjan T F BeekmanRalph W KupkaPublished in: Bipolar disorders (2021)
Differences in clinical characteristics across stages support the construct validity of both staging models. Characteristics associated with a higher stage largely overlapped across both models. This study is a first step toward determining different clinical profiles, with a corresponding course and outcome.