Impact of NTRK2, DRD2 and ACE polymorphisms on prolactin levels in antipsychotic-treated patients with first-episode psychosis.

Patricia GassóSergi MasMiquel BioqueBibiana CabreraAntonio LoboAna González-PintoCovadonga M Díaz-CanejaIluminada CorripioEduard VietaJosefina Castro-FornielesSalvador SarróAnna ManéJulio SanjuanAdrián LlerenaAmalia LafuenteJerónimo Saiz-RuizMiguel Bernardonull null

Published in: Journal of psychopharmacology (Oxford, England) (2018)

Our results give more support to the impact of DRD2, but also of other genes related to dopamine availability such as ACE. Moreover, this study provides the first evidence for the involvement of NTRK2, which suggests that pathways other than the ones related to dopamine or serotonin may participate in the AP-related PRL levels.

Keyphrases

angiotensin ii
uric acid
angiotensin converting enzyme
gene expression
genome wide