Trastuzumab emtansine with or without pertuzumab versus trastuzumab with taxane for human epidermal growth factor receptor 2-positive advanced breast cancer: Final results from MARIANNE.

Edith A PerezCarlos BarriosWolfgang EiermannMasakazu ToiYoung-Hyuck ImPierfranco ConteMiguel MartinTadeusz PienkowskiXavier B PivotHoward A BurrisJennifer A PetersenSanne De HaasSilke HoerschMonika PatrePaul Anthony Ellis

Published in: Cancer (2019)

These results support T-DM1 as a first-line treatment for patients with HER2-positive metastatic breast cancer who are deemed unsuitable for taxane-based therapy.

Keyphrases

metastatic breast cancer
epidermal growth factor receptor
tyrosine kinase
advanced non small cell lung cancer
endothelial cells
induced pluripotent stem cells
stem cells
type diabetes
adipose tissue
metabolic syndrome
weight loss
insulin resistance