Association of interpregnancy change in body mass index and spina bifida.
Renata H BenjaminMary K EthenMark A CanfieldFei HuaLaura E MitchellPublished in: Birth defects research (2019)
Our findings provide suggestive, although not conclusive, evidence that maternal prepregnancy change in BMI, assessed using IPC-BMI, is associated with spina bifida in the later pregnancy. Additional studies aimed at confirming this association and further strengthening the evidence for a causal relationship between spina bifida and maternal BMI are needed.