Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers.
Pan ShuTing ZhaoBo WenKari Mendelsohn-VictorDuxin SunChristopher R FrieseManjunath Amit P PaiPublished in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2019)
Development of a sensitive high-throughput multi-analyte cancer chemotherapy assay is feasible using an MRM-IDA-EPI method. This method can be used to rapidly rule out systemic exposure to accidental acute chemotherapy spills in health care workers.
Keyphrases
- high throughput
- liquid chromatography tandem mass spectrometry
- liver failure
- locally advanced
- drug induced
- respiratory failure
- simultaneous determination
- single cell
- ms ms
- papillary thyroid
- squamous cell carcinoma
- rectal cancer
- chemotherapy induced
- solid phase extraction
- young adults
- high resolution
- mass spectrometry
- childhood cancer
- liquid chromatography