Abnormal dynamic functional connectivity of hippocampal subregions associated with working memory impairment in melancholic depression.
Shunkai LaiTing SuShuming ZhongGuangmao ChenYiliang ZhangHui ZhaoPan ChenGuixian TangZhangzhang QiJiali HeYunxia ZhuSihui LvZijin SongHaofei MiaoYilei HuYanbin JiaYing WangPublished in: Psychological medicine (2021)
These findings confirmed the distinct dynamic functional pathway of hippocampal subregions in patients with melancholic MDD, and suggested that the dysfunction of hippocampus-cerebellum connectivity may be underlying the neural substrate of working memory impairment in melancholic MDD.
Keyphrases
- working memory
- functional connectivity
- resting state
- major depressive disorder
- cerebral ischemia
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- depressive symptoms
- subarachnoid hemorrhage
- bipolar disorder
- blood brain barrier
- oxidative stress
- cognitive impairment
- brain injury
- white matter
- multiple sclerosis
- physical activity
- amino acid
- prefrontal cortex