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Isolated premature restriction or closure of foramen ovale in fetuses: Echocardiographic characteristics and outcome.

Xiaoyan GuYe ZhangJian-Cheng HanXiaowei LiuShuping GeYihua He
Published in: Echocardiography (Mount Kisco, N.Y.) (2018)
Premature rFO/cFO are rare in fetuses with otherwise structurally normal hearts. The fetal echocardiographic characteristics include right atrial and ventricular dilated, tricuspid regurgitation, and pericardial effusion. Most fetuses had a good outcome, although there was an association between rFO, especially cFO, with neonatal morality and complications (prematurity, maternal preeclampsia and placental abruption, hydrops fetalis, and necrotizing enterocolitis with perforation).
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