Clarithromycin hypersensitivity in children: Is there a link with β-lactam hypersensitivity?

Ayse Suleyman Esra Ozek Yucel Sevgi Sipahi Cimen Zeynep Hızlı Demirkale Cevdet Özdemir Zeynep Ulker Tamay Nermin Güler

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)

The frequency of confirmed clarithromycin hypersensitivity was found low among suspected patients. Oral provocation test is crucial for definite diagnosis. Confirmed β-lactam allergy may be attributed as a risk factor for clarithromycin hypersensitivity, particularly clarithromycin treatment after a developing rash with amoxicillin-clavulanic acid in sequential usage.

Keyphrases

helicobacter pylori
helicobacter pylori infection
drug induced
end stage renal disease
newly diagnosed
prognostic factors
peritoneal dialysis
pulmonary embolism
gram negative
patient reported outcomes
atopic dermatitis